What is PubMed?
PubMed comprises more than 26 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
The brilliant thing about PubMed is that all scientific publishers whatever their ranking publishes at PubMed too- so it is comprised of everything- the latest greatest that we do not understand since written by and for scientists, but also the simple stuff which can be very enlightening for every mortal.
Anyway- to me- this query is pretty brilliant- it is on "Adipose + Derived + Regeneretive + Cells" and withe restriction- free papers only!
The below is the result of the day... i.e. come back often, since the listing of this page changes often....
Below you will find the feed of the latest "Free articles" with theme: Adipose Derived Regeneretive Cells"- i.e. ADRCs...
Stem cell therapy for abrogating stroke-induced neuroinflammation and relevant secondary cell death mechanisms.
Prog Neurobiol. 2017 Nov;158:94-131
Authors: Stonesifer C, Corey S, Ghanekar S, Diamandis Z, Acosta SA, Borlongan CV
Ischemic stroke is a leading cause of death worldwide. A key secondary cell death mechanism mediating neurological damage following the initial episode of ischemic stroke is the upregulation of endogenous neuroinflammatory processes to levels that destroy hypoxic tissue local to the area of insult, induce apoptosis, and initiate a feedback loop of inflammatory cascades that can expand the region of damage. Stem cell therapy has emerged as an experimental treatment for stroke, and accumulating evidence supports the therapeutic efficacy of stem cells to abrogate stroke-induced inflammation. In this review, we investigate clinically relevant stem cell types, such as hematopoietic stem cells (HSCs), mesenchymal stem cells (MSCs), endothelial progenitor cells (EPCs), very small embryonic-like stem cells (VSELs), neural stem cells (NSCs), extraembryonic stem cells, adipose tissue-derived stem cells, breast milk-derived stem cells, menstrual blood-derived stem cells, dental tissue-derived stem cells, induced pluripotent stem cells (iPSCs), teratocarcinoma-derived Ntera2/D1 neuron-like cells (NT2N), c-mycER(TAM) modified NSCs (CTX0E03), and notch-transfected mesenchymal stromal cells (SB623), comparing their potential efficacy to sequester stroke-induced neuroinflammation and their feasibility as translational clinical cell sources. To this end, we highlight that MSCs, with a proven track record of safety and efficacy as a transplantable cell for hematologic diseases, stand as an attractive cell type that confers superior anti-inflammatory effects in stroke both in vitro and in vivo. That stem cells can mount a robust anti-inflammatory action against stroke complements the regenerative processes of cell replacement and neurotrophic factor secretion conventionally ascribed to cell-based therapy in neurological disorders.
PMID: 28743464 [PubMed - indexed for MEDLINE]