What are Mesenchymal Stem Cells?
Mesenchymal stem cells (MSCs) are a prototypical adult stem cell with capacity for self-renewal and differentiation with a broad tissue distribution. Initially described in bone marrow, MSCs have the capacity to differentiate into mesoderm- and nonmesoderm-derived tissues. The endogenous role for MSCs is maintenance of stem cell niches (classically the hematopoietic), and as such, MSCs participate in organ homeostasis, wound healing, and successful aging. From a therapeutic perspective, and facilitated by the ease of preparation and immunologic privilege, MSCs are emerging as an extremely promising therapeutic agent for tissue regeneration. Studies in animal models of myocardial infarction have demonstrated the ability of transplanted MSCs to engraft and differentiate into cardiomyocytes and vasculature cells, recruit endogenous cardiac stem cells, and secrete a wide array of paracrine factors.
Together, these properties can be harnessed to both prevent and reverse remodeling in the ischemically injured ventricle. In proof-of-concept and phase I clinical trials, MSC therapy improved left ventricular function, induced reverse remodeling, and decreased scar size.
The above is a "careful" assessment by Joshua Hare- cardiologist, but despite thousands of studies "the medical establishment" is not yet totally convinced. The image you see, is what has been proven to happen upon injury by the godfather of MSCs- Arnold Caplan-i.e. activation of MSC precursers or pericytes from the outer walls of arteries to "come to the rescue" after injury and at the same time building a wall around the area to prevent run-a-way inflammation and attacks by own T-cells.
MSCs are because of the above fact (lined at the outer walls of arteries) so relevant to Fat Cells- since adipose tissue is a highly vascularized tissue, hence contains so many MSC precursers.
Lung Disease NewsNorth Carolina Advances in Stem Cell Therapy for Lung Diseases Could Lead to Clinical Trial Soon
Lung Disease News
University of North Carolina Health Care researchers have made strides toward a stem cell treatment for lung diseases such as pulmonary fibrosis, COPD, and cystic fibrosis. In fact, they are discussing the start of clinical trials with regulatory ...
Stem Cell Treatments for Lung Diseases Advance
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Publicist Report - Market Research News by Market.BizStem Cell Therapy Educational Seminars
Checkbiotech.org (press release)
Cord tissue mesenchymal stem cells have a faster doubling time than adult mesenchymal stem cells (because they are younger and contain a higher concentration of growth factors)The fitness of adult mesenchymal stem cells declines with age. Thus, cord ...
Young Patient With Autism Improves After Stem Cell Therapy Program
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Stem Cell Assay Market Personalized LASIK Surgery Market Size will Grow at a Lucrative CAGR through 2025
Stem cells can differ from other types of cells in the body. There are two types of stem cells namely the embryonic stem cells and adult stem cells. Adult stem cells comprise of hematopoietic, mammary, intestinal, neural, mesenchymal stem cells, etc ...
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The ScientistStem Cells Seek Out Tumors Based on Stiffness
The collagen network (cyan) serves as a biophysical biomarker of cancerous cells (red).LINAN LIU & JENU V. CHACKOFor the first time, researchers have genetically engineered mesenchymal stem cells (MSCs) to deliver a therapeutic to tumor cells based ...
Mesenchymal stem cells market grows with increasing clinical application for the treatment of chronic disease...
Global Mesenchymal Stem Cells Market is estimated to reach XX Million USD in 2017 – 2022
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Application Note: Characterization of Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) are fibroblastoid multipotent adult stem cells with a high capacity for self-renewal, and have been isolated from a variety of human tissues. This poster defines three criteria developed by the International Society for ...
American CryoStem Corporation Announces Financial Results for Q3 Fiscal 2017
Anthony Dudzinski, COO stated, "We have seen a continued increase in our processing volume revenue for our ATGRAFT tissue storage platform, as well as from individuals storing their stem cells during the quarter ended June 30, 2017. This revenue ...
Pre-Existing Inflammatory Diseases Reduce Therapeutic Potential of Stem Cells for MS Treatment, Study Shows
Multiple Sclerosis News Today
Pre-existing inflammatory diseases affecting the central nervous system make mesenchymal stem cells (MSCs) less effective in treating multiple sclerosis (MS), concludes a study by researchers at Cleveland's Case Western Reserve University School of ...
Ask the Doctors: Stem cell therapy may help worn-out knees
Berkshire Eagle (subscription)
The intriguing thing about stem cells is that they have the ability to become any type of cell that the body needs. The cells used for stem cell injections in the knees are called mesenchymal stem cells, and they can differentiate into bone, fat or ...
Under The Microscope: UTC Honors College Student Working On Nanotechnology In Japan
Mesenchymal stem cells. Cooper Thome is working with mesenchymal stem cells. What the heck are mesenchymal stem cells? In regular folks terms, they're stem cells that can grow into a variety of different cells, from bone to cartilage, from muscle to fat.
Citizens VoiceStem cell therapy may help knees - News - Citizens' Voice
Q: I read that you can use your own stem cells to rejuvenate worn-out knees. Does this really work? A: “Worn out” is a good way to term what happens to the ...
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